circRNA basic information
circBase ID: hsa_circ_0007444
Name: hsa_circ_RHOBTB3
Synonym: circRHOBTB3
Host Gene: -
 
 
 
Disease basic information
DO ID:
4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: CC cell lines (SiHa, HeLa, C33A, CaSki), normal human cervical cell line (HCerEpiC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NR1H4, IGF2BP3
Associated microRNA: -
Biological function: circRHOBTB3 knockdown also repressed CC proliferation, migration, invasion, and the Warburg effects
Molecular mechanism: NR1H4/circRHOBTB3/IGF2BP3 axis
Survival: -
Supported No.:
1
Description:

In conclusion, this novel NR1H4/circRHOBTB3/IGF2BP3 axis may provide new insights into CC pathogenesis.

Other information
Title:

NR1H4-mediated circRHOBTB3 modulates the proliferation, metastasis, and Warburg effects of cervical cancer through interacting with IGF2BP3.

Journal: Mol Cell Biochem
Published: 2023/3/21
PubMed ID: 36939994