circRNA basic information
circBase ID: hsa_circ_0000240
Name: hsa_circ_CCAR1
Synonym: circCCAR1
Host Gene: hsa-miR-127-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: WTAP
Associated microRNA: hsa-miR-127-5p
Biological function: CircCCAR1 accelerated the growth and metastasis of HCC in vitro and in vivo
Molecular mechanism: circCCAR1/hsa-miR-127-5p/WTAP axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

The circCCAR1/miR-127-5p/WTAP feedback loop enhances the growth and metastasis of HCC.
Other information
Title:

Exosome-derived circCCAR1 promotes CD8 + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma.

Journal: Mol Cancer
Published: 2023/3/19
PubMed ID: 36932387