circRNA basic information
circBase ID: hsa_circ_0004592
Name: hsa_circ_STK3
Synonym: circSTK3
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: CTCF
Associated microRNA: -
Biological function: Loss- and gain-of-function assays revealed that circSTK3 promoted the migration and invasion but not proliferation of cells
Molecular mechanism: EMT programming
Survival: -
Supported No.:
 1
Description:

These findings reveal the functional and prognostic roles of circSTK3 and expose circRNAs as key players in metastasis.
Other information
Title:

CircSTK3 drives the metastasis of colorectal cancer by regulating epithelial-mesenchymal transition.

Journal: iScience
Published: 2023/3/17
PubMed ID: 36922993