circRNA basic information
circBase ID: hsa_circ_0005615
Name: hsa_circ_NFATC3
Synonym: circ_0005615
Host Gene: hsa-miR-873-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human CRC cell lines (HCT116, LOVO, SW480), human normal colorectal mucous membrane cell-line (FHC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOSL2
Associated microRNA: hsa-miR-873-5p
Biological function: Circ_0005615 knockdown inhibited cell proliferation, migration, and invasion, whereas promoted cell apoptosis in CRC
Molecular mechanism: circ_0005615/hsa-miR-873-5p/FOSL2 axis, miRNA sponge
Survival: -
Supported No.:
 3
Description:

Circ_0005615 modulated CRC malignant progression by controlling FOSL2 expression through sponging miR-873-5p.
Other information
Title:

Circ_0005615 Regulates the Progression of Colorectal Cancer Through the miR-873-5p/FOSL2 Signaling Pathway.

Journal: Biochem Genet
Published: 2023/3/16
PubMed ID: 36920708