circRNA basic information
circBase ID: hsa_circ_0001361
Name: hsa_circ_FNDC3B
Synonym: circ_0001361
Host Gene: hsa-miR-490-5p
 
 
 
Disease basic information
DO ID:
 769
DO name: neuroblastoma
Disease details: neuroblastoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: IMR-32, SK-N-SH cells, as well as human umbilical vein endothelial cell line (HUVEC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TRIM2
Associated microRNA: hsa-miR-490-5p
Biological function: Hsa_circ_0001361 downregulation suppressed cell proliferation, metastasis and glycolysis.
Molecular mechanism: Hsa_circ_0001361/hsa-miR-490-5p/TRIM2 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Our results suggested that hsa_circ_0001361 upregulated TRIM2 by absorbing miR-490-5p, thereby promoting cell malignant behaviors and glycolytic metabolism in NB.
Other information
Title:

Hsa_circ_0001361 facilitates cell progression and glycolytic metabolism in neuroblastoma via interacting with mir-490-5p to induce TRIM2 upregulation.

Journal: Metab Brain Dis
Published: 2023/3/16
PubMed ID: 36920626