circRNA basic information
circBase ID: hsa_circ_0007429
Name: hsa_circ_RREB1
Synonym: circ_0007429
Host Gene: hsa-miR-637
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: HCC
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal liver cell line (LO2), HCC cell lines (Huh7, HepG2, HCCL-M3, SK-HEP1, Hep3B, MHCC97H)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TRIM71, Ago2
Associated microRNA: hsa-miR-637
Biological function: Knockdown of circ_0007429 enhanced apoptosis in HCC cells, while impeded proliferation, migration, invasion, and aerobic glycolysis
Molecular mechanism: circ_0007429/hsa-miR-637/TRIM71, Ago2 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0007429 promotes HCC progression by promoting cell proliferation, migration, invasion, and aerobic glycolysis and by inhibiting cell apoptosis through the miR/TRIM71/Ago2 axis.
Other information
Title:

Circ_0007429/miR-637/TRIM71/Ago2 axis participates in the regulation of proliferation, migration, invasion, apoptosis, and aerobic glycolysis of HCC.

Journal: Mol Carcinog
Published: 2023/3/16
PubMed ID: 36920046