circRNA basic information
circBase ID: hsa_circ_0005273
Name: hsa_circ_PTK2
Synonym: circPTK2
Host Gene: hsa-miR-619
 
 
 
Disease basic information
DO ID:
10591
DO name: pre-eclampsia
Disease details: preeclampsia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: WNT7B
Associated microRNA: hsa-miR-619
Biological function: CircPTK2 silencing inhibited HTR-8/SVneo growth and migration in vitro
Molecular mechanism: circPTK2/hsa-miR-619/WNT7B axis, miRNA sponge
Survival: -
Supported No.:
1
Description:

To conclude, this study identified the functions and mechanisms of the circPTK2/miR-619/WNT7B axis in PE progression.

Other information
Title:

circPTK2 promotes proliferation, migration and invasion of trophoblast cells through the miR-619/WNT7B pathway in preeclampsia.

Journal: Mol Cell Biochem
Published: 2023/3/14
PubMed ID: 36913151