circRNA basic information
circBase ID: hsa_circ_0084912
Name: hsa_circ_KIAA1429
Synonym: circ_0084912
Host Gene: hsa-miR-429
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human cervical epithelial immortalized cell line (End1/E6E7), 4 human CC cell lines (Hela, SiHa, CaSki, C33A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOX2
Associated microRNA: hsa-miR-429
Biological function: Silencing hsa_circ_0084912 inhibited cell proliferation, colony formation and migration in vitro of CC, meanwhile reducing growth of tumor in vivo
Molecular mechanism: circ_0084912/hsa-miR-429/SOX2 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

By raising SOX2 expression by targeting miR-429, hsa_circ_0084912 accelerated the development of CC, offering fresh proof that it is a viable target for CC treatment.
Other information
Title:

Hsa_circ_0084912 Drives the Progression of Cervical Cancer Via Regulating miR-429/SOX2 Pathway.

Journal: Mol Biotechnol
Published: 2023/3/14
PubMed ID: 36913084