circRNA basic information
circBase ID: hsa_circ_0078607
Name: hsa_circ_SLC22A3
Synonym: circ_0078607
Host Gene: hsa-miR-196b-5p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: OC cell lines (A2780, SKOV3), normal ovarian epithelial cells (IOSE-80)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: GAS7
Associated microRNA: hsa-miR-196b-5p
Biological function: Overexpression of circ_0078607 inhibited DDP resistance, cell growth and induced apoptosis in DDP-resistant OC cells
Molecular mechanism: circ_0078607/hsa-miR-196b-5p/GAS7 axis, miRNA sponge
Survival: -
Supported No.:
 4
Description:

Circ_0078607 attenuates DDP resistance via miR-196b-5p/GAS7 axis, which highlights the therapeutic potential of circ_0078607 to counter DDP resistance in OC.
Other information
Title:

Circ_0078607 increases platinum drug sensitivity via miR-196b-5p/GAS7 axis in ovarian cancer.

Journal: Epigenetics
Published: 2023/3/14
PubMed ID: 36908025