circRNA basic information
circBase ID: hsa_circ_0064644
Name: hsa_circ_RBMS3
Synonym: circRBMS3
Host Gene: hsa-miR-424
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human OS cell lines (HOS, 143B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: eIF4B, YRDC
Associated microRNA: hsa-miR-424
Biological function: ShcircRBMS3 inhibits the proliferation and migration of osteosarcoma cells
Molecular mechanism: circRBMS3/hsa-miR-424-5p/eIF4B/YRDC axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Our results reveal an important role for a novel circRBMS3 in the growth and metastasis of malignant tumor cells and offer a fresh perspective on circRNAs in OS progression.
Other information
Title:

A novel circular RNA circRBMS3 regulates proliferation and metastasis of osteosarcoma by targeting miR-424-eIF4B/YRDC axis.

Journal: Aging (Albany NY)
Published: 2023/3/11
PubMed ID: 36897170