circRNA basic information
circBase ID: hsa_circ_0107595
Name: hsa_circ_ABCA5
Synonym: circABCA5
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human gastric cancer cell lines (MKN-45, GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IL6, JAK2, STAT3, EIF4A3
Associated microRNA: -
Biological function: circABCA5 could promote gastric cancer proliferation, invasion, and migration in vitro and in vivo
Molecular mechanism: circABCA5/IL6/JAK2/STAT3/EIF4A3 axis
Survival: -
Supported No.:
 1
Description:

Our study reveals that circABCA5 plays a vital role in the diagnosis and prognosis of gastric cancer and may even be developed as a molecular target for the treatment of gastric cancer.
Other information
Title:

EIF4A3 induced circABCA5 promotes the gastric cancer progression by SPI1 mediated IL6/JAK2/STAT3 signaling.

Journal: Am J Cancer Res
Published: 2023/3/11
PubMed ID: 36895988