circRNA basic information
circBase ID: hsa_circ_0085803
Name: hsa_circ_TSNARE1
Synonym: circRNA-104718
Host Gene: hsa-miR-218-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGB1
Associated microRNA: hsa-miR-218-5p
Biological function: Knockdown of circRNA-104718 suppressed migration and invasion while boosting the apoptosis rate of glioma cells.
Molecular mechanism: circRNA-104718/hsa-miR-218-5p/HMGB1 axis, miRNA sponge
Survival: poor
Supported No.:
 1
Description:

CircRNA-104718 modulates glioma cell proliferation through the miR-218-5p/HMGB1 signalling axis. CircRNA-104718 provides a possible mechanism for understanding the pathogenesis of glioma.
Other information
Title:

CircRNA-104718 promotes glioma malignancy through regulation of miR-218-5p/HMGB1 signalling pathway.

Journal: Metab Brain Dis
Published: 2023/3/4
PubMed ID: 36867300