circRNA basic information
circBase ID: hsa_circ_0071803
Name: hsa_circ_SEMA5A
Synonym: circ_0071803
Host Gene: hsa-miR-330-5p
 
 
 
Disease basic information
DO ID:
9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Four human CRC cell lines (SW620, HT-29, HCT116, LoVo), a human normal colon cell line (NCM460)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MAPK
Associated microRNA: hsa-miR-330-5p
Biological function: circ_0071803 knockdown suppressed cell proliferation, migration, and invasion in CRC
Molecular mechanism: circ_0071803/hsa-miR-330-5p/MAPK axis, miRNA sponge
Survival: -
Supported No.:
2
Description:

Collectively, our findings elucidate that circ_0071803 promotes CRC progression by regulating the miR-330-5p/MAPK1 pathway, providing potential therapeutic targets for designing effective targeted treatments.

Other information
Title:

Has_circ_0071803 promotes colorectal cancer progression by regulating miR-330-5p/MAPK signaling pathway.

Journal: Histol Histopathol
Published: 2023/3/2
PubMed ID: 36856372