circRNA basic information
circBase ID: hsa_circ_0072309
Name: hsa_circ_LIFR
Synonym: circ_0072309
Host Gene: hsa-miR-34a-3p, hsa-miR-330-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
S
M
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-34a-3p, hsa-miR-330-5p
Biological function: The real-time quantitative PCR (RT-qPCR) results revealed a significant downregulation of hsa_circ_0072309 in GC tissues related to tumor size, vascular invasion, and lymph node metastasis. A hsa_circ_0072309 overexpression suppressed whereas a hsa_circ_0072309 knockdown promoted GC cells proliferation and migration in vitro
Molecular mechanism: -
Survival: -
Supported No.:
 2
Description:

Hsa_circ_0072309 is a potential diagnostic biomarker for GC, and complement component 7 may be a tumor suppressor. These may potentially predict the prognosis of patients with GC and may become new therapeutic targets.
Other information
Title:

Hsa_circ_0072309 is a prognostic biomarker and is correlated with immune infiltration in gastric cancer.

Journal: Heliyon
Published: 2023/3/1
PubMed ID: 36852074