circRNA basic information
circBase ID: hsa_circ_0010023
Name: hsa_circ_DHRS3
Synonym: circDHRS3
Host Gene: hsa-miR-421
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: RWPE-1, BPH-1, prostate cancer cell lines (22Rv1, PC3, Du145)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: MEIS2
Associated microRNA: hsa-miR-421
Biological function: overexpression of circDHRS3 could inhibit both the lung and bone metastasis of prostate cancer cells
Molecular mechanism: circDHRS3/hsa-miR-421/MEIS2 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Our study indicates that circDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis.
Other information
Title:

CircDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis.

Journal: Epigenetics
Published: 2023/2/26
PubMed ID: 36840946