circRNA basic information
circBase ID: hsa_circ_0001667
Name: hsa_circ_HEATR2
Synonym: circ_0001667
Host Gene: hsa-miR-6838-5p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human normal breast epithelial cells (MCF-10A), breast cancer cell lines (MDA-MB-468, BT549, MCF-7)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CXCL10
Associated microRNA: hsa-miR-6838-5p
Biological function: circ_0001667 knockdown inhibited proliferation and angiogenesis of breast cancer cells
Molecular mechanism: circ_0001667/hsa-miR-6838-5p/CXCL10 axis, miRNA sponge
Survival: -
Supported No.:
 4
Description:

Circ_0001667 is involved in breast cancer cell proliferation and angiogenesis through regulation of the miR-6838-5p/CXCL10 axis.
Other information
Title:

Circ_0001667 accelerates breast cancer proliferation and angiogenesis through regulating CXCL10 expression by sponging miR-6838-5p.

Journal: Thorac Cancer
Published: 2023/2/23
PubMed ID: 36811283