circRNA basic information
circBase ID: hsa_circ_0137652
Name: hsa_circ_RAD23B
Synonym: circ_0137652
Host Gene: hsa-miR-1205
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human BC cell lines (MDA-MB-468, MDA-MB-231, MCF-7), normal human mammary epithelial cells (MCF-10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CCNB1
Associated microRNA: hsa-miR-1205
Biological function: silencing circ_0137652, the growth and migration of BC cells were reduced. Animal experiments showed that circ_0137652 hampers the tumorigenesis of BC cells in vivo
Molecular mechanism: circ_0137652/hsa-miR-1205/CCNB1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0137652 controls the miR-1205/CCNB1 axis to induce increased breast cancer malignancy.
Other information
Title:

Hsa_circ_0137652 Regulates miR-1205/CCNB1 Axis to Accelerate the Malignancy of Breast Cancer.

Journal: Mol Biotechnol
Published: 2023/2/23
PubMed ID: 36807271