circRNA basic information
circBase ID: -
Name: hsa_circ_ADSS
Synonym: circADSS
Host Gene: hsa-miR-431-5p
 
 
 
Disease basic information
DO ID:
684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Huh7, SNU423, MHCC97H, HCCLM3 cells, liver epithelial cells (THLE-2)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: TOP2A
Associated microRNA: hsa-miR-431-5p
Biological function: CircADSS silencing decreased HCC cell proliferation, cell cycle progression, migration, invasion, as well as EMT
Molecular mechanism: circADSS/hsa-miR-431-5p/TOP2A axis, miRNA sponge
Survival: -
Supported No.:
2
Description:

CircADSS could regulate HCC cell malignancy by miR-431-5p/TOP2A axis.

Other information
Title:

CircADSS contributes to hepatocellular carcinoma development by regulating miR-431-5p/TOP2A.

Journal: Clin Exp Pharmacol Physiol
Published: 2023/2/15
PubMed ID: 36786410