circRNA basic information
circBase ID: hsa_circ_0124208
Name: hsa_circ_TKT
Synonym: circ_0124208
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal hepatic cell line (THLE2), HCC cell lines (Hep 3B, Huh7, SNU-182)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LAMC1
Associated microRNA: hsa-miR-338-3p
Biological function: silencing circ_0124208 attenuated proliferation and migration, but boosted the apoptosis of Hep 3B and Huh7 cells in vitro. The in vivo experiment further validated the repression of tumor growth via circ_0124208 knockdown
Molecular mechanism: circ_0124208/hsa-miR-338-3p/LAMC1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

the circ_0124208/miR-338-3p/LAMC1 axis can be used as a potential therapeutic target for HCC treatment.
Other information
Title:

Circ_0124208 Promotes the Progression of Hepatocellular Carcinoma by Regulating the miR-338-3p/LAMC1 Axis.

Journal: Mol Biotechnol
Published: 2023/2/14
PubMed ID: 36780058