circRNA basic information
circBase ID: hsa_circ_0000025
Name: hsa_circ_EIF4G3
Synonym: circ_000558
Host Gene: hsa-miR-1225-5p
 
 
 
Disease basic information
DO ID:
 4450
DO name: renal cell carcinoma
Disease details: renal cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human RCC cells (ACHN, 786-O, 769-P, Caki-1), human renal epithelial cells (HK2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ARL4C
Associated microRNA: hsa-miR-1225-5p
Biological function: we found circ_000558 was upregulated in RCC cells, and it elevated the proliferation ability of RCC cells
Molecular mechanism: circ_000558/hsa-miR-1225-5p/ARL4C axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Overall, our study suggested that circ_000558/miR-1225-5p/ARL4C network was related to the RCC cell proliferation.
Other information
Title:

The Effects of circ_000558/miR-1225-5p/ARL4C on Regulating the Proliferation of Renal Cell Carcinoma Cells.

Journal: J Oncol
Published: 2023/2/14
PubMed ID: 36778920