circRNA basic information
circBase ID: hsa_circ_0017956
Name: hsa_circ_MLLT10
Synonym: circ_0017956
Host Gene: hsa-miR-758-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human umbilical vein endothelial cells (HUVECs), NSCLC cell lines (A549, H1299), human lung epithelial cell line (BEAS-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXP4
Associated microRNA: hsa-miR-758-3p
Biological function: Silencing of circ_0017956 significantly suppressed cell proliferation, migration, invasion, and angiogenesis, but promoted cell apoptosis in NSCLC cells
Molecular mechanism: circ_0017956/hsa-miR-758-3p/FOXP4 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

Altogether, circ_0017956 promoted the progression of NSCLC by regulating FOXP4 through sponging miR-758-3p.
Other information
Title:

Hsa_circ_0017956 Acts as miR-758-3p Sponge to Facilitate the Progression of Non-small-Cell Lung Cancer by Regulating FOXP4 Expression.

Journal: Mol Biotechnol
Published: 2023/2/11
PubMed ID: 36763305