circRNA basic information
circBase ID: hsa_circ_0084188
Name: hsa_circ_KIAA0146
Synonym: circ_0084188
Host Gene: hsa-miR-769-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HCT116, SW620, normal intestinal epithelial cells NCM460
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KIF20A
Associated microRNA: hsa-miR-769-5p
Biological function: Circ_0084188 knockdown repressed the proliferation, migration, and invasion of CRC cells, as well as enhanced apoptosis in vitro
Molecular mechanism: circ_0084188/hsa-miR-769-5p/KIF20A axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0084188 upregulated the expression of KIF20A to promote the tumorigenesis of CRC through miR-769-5p, providing a new therapeutic target for CRC.
Other information
Title:

Circ_0084188 Regulates the progression of colorectal cancer through the miR-769-5p/KIF20A axis.

Journal: Biochem Genet
Published: 2023/2/11
PubMed ID: 36763221