circRNA basic information
circBase ID: hsa_circ_0024108
Name: hsa_circ_MMP1
Synonym: circ_0024108
Host Gene: hsa-miR-488-3p
 
 
 
Disease basic information
DO ID:
 5041
DO name: esophageal cancer
Disease details: esophageal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: ESCC cell lines (ECA109, KYSE150, KYSE450, KYSE410), normal esophagus epithelial cell line (HET-1A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: USP14
Associated microRNA: hsa-miR-488-3p
Biological function: Deficiency of circ_0024108 impeded cell growth, motility, and invasiveness
Molecular mechanism: circ_0024108/hsa-miR-488-3p/USP14 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Taken together, circ_0024108 participated in the progress of ESCC through the miR-488-3p/USP14 axis. Circ_0024108 was differentially expressed in serum exosomes. Circ_0024108 might be a potential biomarker for the diagnosis of ESCC.
Other information
Title:

Circ_0024108 promotes the progression of esophageal cancer cells.

Journal: Gen Thorac Cardiovasc Surg
Published: 2023/2/10
PubMed ID: 36757626