circRNA basic information
circBase ID: hsa_circ_0063329
Name: hsa_circ_DDX17
Synonym: circ_0063329
Host Gene: hsa-miR-605-5p
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: PCa cell lines (PC-3, 22Rv1, DU145, LNCaP, C4_2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: TGIF2
Associated microRNA: hsa-miR-605-5p
Biological function: A series of in vitro and in vivo functional assays showed that overexpression of hsa_circ_0063329 inhibits PCa cell progression, while silencing of hsa_circ_0063329 achieved the opposite effects
Molecular mechanism: circ_0063329/hsa-miR-605-5p/TGIF2 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

In conclusion, hsa_circ_0063329 inhibits the proliferation and metastasis of PCa via modulation of the miR-605-5p/TGIF2 axis, and targeting hsa_circ_0063329 may provide a promising treatment strategy for aggressive PCa.
Other information
Title:

Hsa_circ_0063329 inhibits prostate cancer growth and metastasis by modulating the miR-605-5p/tgif2 axis.

Journal: Cell Cycle
Published: 2023/2/7
PubMed ID: 36740902