circRNA basic information
circBase ID: hsa_circ_0000285
Name: hsa_circ_HIPK3
Synonym: circ_0000285
Host Gene: hsa-miR-1278
 
 
 
Disease basic information
DO ID:
 9261
DO name: nasopharynx carcinoma
Disease details: nasopharyngeal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human normal nasopharyngeal epithelial cells (NP69), NPC cell lines (HK1, C666-1, 5_8F, SUNE-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FNDC3B
Associated microRNA: hsa-miR-1278
Biological function: Knockdown of circ_0000285 inhibited NPC cell proliferation, migration, invasion, and while promoting NPC cell apoptosis in vitro.
Molecular mechanism: circ_0000285/hsa-miR-1278/FNDC3B axis, miRNA sponge
Survival: -
Supported No.:
 3
Description:

Circ_0000285 upregulates FNDC3B expression by adsorbing miR-1278 to promote NPC development.
Other information
Title:

Circ_0000285 regulates nasopharyngeal carcinoma progression through miR-1278/FNDC3B axis.

Journal: Hum Exp Toxicol
Published: 2023/2/5
PubMed ID: 36738165