circRNA basic information
circBase ID: hsa_circ_0013613
Name: hsa_circ_AP4B1
Synonym: circ_0013613
Host Gene: hsa-miR-370-3p
 
 
 
Disease basic information
DO ID:
319
DO name: spinal cord disease
Disease details: spinal cord injury
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: caspase1
Associated microRNA: hsa-miR-370-3p
Biological function: Knockdown of circ_0013613 suppressed LPS-stimulated cytotoxicity, inflammation and inflammation-induced pyroptosis.
Molecular mechanism: circ_0013613/hsa-miR-370-3p/caspase1 axis, miRNA sponge
Survival: -
Supported No.:
1
Description:

circ_0013613 can promote the recovery of SCI by regulating miR-370-3p/CASP1 to mediate neuronal pyroptosis.

Other information
Title:

circ_0013613 Promotes the recovery of spinal cord injury by regulating mir-370-3p/caspase1 to regulate neuronal pyroptosis.

Journal: Acta Biochim Pol
Published: 2023/2/4
PubMed ID: 36735415