circRNA basic information
circBase ID: hsa_circ_0005667
Name: hsa_circ_ZNF124
Synonym: circ_0005667
Host Gene: hsa-miR-145-5p
 
 
 
Disease basic information
DO ID:
 1380
DO name: endometrial cancer
Disease details: endometrial cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IGF2BP1
Associated microRNA: hsa-miR-145-5p
Biological function: The circ_0005667 deficiency could enhance DDP sensitivity, inhibit cell proliferation, migration and invasion and promote cell apoptosis in DDP-resistant EC cells in vitro.
Molecular mechanism: circ_0005667/hsa-miR-145-5p/IGF2BP1 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

Circ_0005667 enhanced DDP resistance in EC by elevating IGF2BP1 through sponging miR-145-5p.
Other information
Title:

Circular RNA circ_0005667 promotes cisplatin resistance of endometrial carcinoma cells by regulating IGF2BP1 through miR-145-5p.

Journal: Anticancer Drugs
Published: 2023/2/3
PubMed ID: 36728962