circRNA basic information
circBase ID: hsa_circ_0008035
Name: hsa_circ_EXT1
Synonym: circ_0008035
Host Gene: hsa-miR-302a
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human gastric adenocarcinoma cell lines (SNU1, AGS), human gastric epithelial cell lines (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: E2F7
Associated microRNA: hsa-miR-302a
Biological function: -
Molecular mechanism: circ_0008035/hsa-miR-302a/E2F7 axis, miRNA sponge
Survival: -
Supported No.:
 4
Description:

Taken together, DEX mediated ferroptotic cell death in GC through regulating the circ0008035/miR-302a/E2F7 axis, suggesting a feasible therapy option for GC.
Other information
Title:

Dexmedetomidine promotes ferroptotic cell death in gastric cancer via hsa_circ_0008035/miR-302a/E2F7 axis.

Journal: Kaohsiung J Med Sci
Published: 2023/2/1
PubMed ID: 36718915