circRNA basic information
circBase ID: hsa_circ_0012673
Name: hsa_circ_DHCR24
Synonym: -
Host Gene: hsa-miR-22
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: ErbB3
Associated microRNA: hsa-miR-22
Biological function: -
Molecular mechanism: suppressing hsa-miR-22, which targets ErbB3
Survival: -
Supported No.:
 2
Description:

Furthermore, hsa_circ_0012673 was primarily localized in the cytoplasm and promoted cell proliferation of LAC cells by sponging miR-22, which targeted erb-b2 receptor tyrosine kinase 3 (ErbB3) in LAC. Hsa_circ_0012673 promotes LAC proliferation by suppressing miR-22, which targets ErbB3.
Other information
Title:

Increased circular RNA hsa_circ_0012673 acts as a sponge of miR-22 to promote lung adenocarcinoma proliferation.

Journal: Biochem Biophys Res Commun
Published: 2018/1/26
PubMed ID: 29366790