circRNA basic information
circBase ID: hsa_circ_0110498
Name: hsa_circ_MAGI3
Synonym: circ_0110498
Host Gene: hsa-miR-1287-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NSCLC cell lines (A549, H1299), human bronchial epithelioid cell line (16HBE)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RBBP4
Associated microRNA: hsa-miR-1287-5p
Biological function: Circ_0110498 silencing not only suppressed the DDP resistance of NSCLC cells by inhibiting cell growth, metastasis and glycolysis, but also enhanced the DDP sensitivity of NSCLC tumors.
Molecular mechanism: circ_0110498/hsa-miR-1287-5p/RBBP4 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

Circ_0110498 facilitated DDP resistance partly through mediating the miR-1287-5p/RBBP4 signaling in NSCLC.
Other information
Title:

Circ_0110498 facilitates the cisplatin resistance of non-small cell lung cancer by mediating the miR-1287-5p/RBBP4 axis.

Journal: Thorac Cancer
Published: 2023/1/25
PubMed ID: 36691322