circRNA basic information
circBase ID: hsa_circ_0001658
Name: hsa_circ_ARID1B
Synonym: circ_0001658
Host Gene: hsa-miR-590-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: CRC cell line (HT29, SW480, LoVo, DLD-1), normal colonic epithelial cell line (FHC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: METTL3
Associated microRNA: hsa-miR-590-5p
Biological function: Circ_0001658 overexpression promoted the proliferation of HT29 cells, inhibited apoptosis, and accelerated the cell cycle. In SW480 cells, knocking down circ_0001658 had the opposite effect.
Molecular mechanism: circ_0001658/hsa-miR-590-5p/METTL3 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0001658 regulates the miR-590-5p/METTL 3-axis to increase CRC cell growth and decrease apoptosis.
Other information
Title:

Hsa_circ_0001658 accelerates the progression of colorectal cancer through miR-590-5p/METTL3 regulatory axis.

Journal: World J Gastrointest Oncol
Published: 2023/1/24
PubMed ID: 36684043