circRNA basic information
circBase ID: hsa_circ_0043256
Name: hsa_circ_ACACA
Synonym: circ_0043256
Host Gene: hsa-miR-1206
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human lung cancer cells (PC9, A549), normal human bronchial epithelial cell (Beas-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: KLF2
Associated microRNA: hsa-miR-1206
Biological function: forced expression of circ_0043256 suppressed lung cancer cell growth, angiopoiesis, migration, and invasion
Molecular mechanism: circ_0043256/hsa-miR-1206/KLF2 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

Forced expression of circ_0043256 could impede the tumorigenesis of lung cancer via miR-1206/KLF2 axis, indicating a potential therapeutic approach for lung cancer.
Other information
Title:

Circ_0043256 upregulates KLF2 expression by absorbing miR-1206 to suppress the tumorigenesis of lung cancer.

Journal: Thorac Cancer
Published: 2023/1/22
PubMed ID: 36680456