circRNA basic information
circBase ID: hsa_circ_0008673
Name: hsa_circ_BRCA1
Synonym: circ_0008673
Host Gene: hsa-miR-578
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: BC cell lines (MDA-MB-231, BT-549, MCF-7, T47D), nontumorous cell line (MCF-10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GINS4
Associated microRNA: hsa-miR-578
Biological function: Hsa_circ_0008673 silencing repressed BC cell growth, metastasis and angiogenesis, as well as hampered BC tumor growth.
Molecular mechanism: circ_0008673/hsa-miR-578/GINS4 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

Hsa_circ_0008673 might promote BC progression via modulating miR-578/GINS4 pathway.
Other information
Title:

Hsa_circ_0008673 Promotes Breast Cancer Progression by MiR-578/GINS4 Axis.

Journal: Clin Breast Cancer
Published: 2023/1/12
PubMed ID: 36628810