circRNA basic information
circBase ID: hsa_circ_0004721
Name: hsa_circ_HGS
Synonym: CircHGS
Host Gene: hsa-miR-513a-5p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: VEGFC
Associated microRNA: hsa-miR-513a-5p
Biological function: In vitro experiments were conducted to detect the effects of circHGS on cell cycle, proliferation, migration and invasion.
Molecular mechanism: circHGS/hsa-miR-513a-5p/VEGFC axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Our findings indicated that circHGS promotes BCa progression via the miR-513a-5p/VEGFC/AKT/mTOR pathway and can be a promising therapeutic target of BCa.
Other information
Title:

CircHGS enhances the progression of bladder cancer by regulating the miR-513a-5p/VEGFC axis and activating the AKT/mTOR signaling pathway.

Journal: Cell Cycle
Published: 2023/1/10
PubMed ID: 36617735