circRNA basic information
circBase ID: hsa_circ_0097009
Name: hsa_circ_SLC5A8
Synonym: circ_0097009
Host Gene: hsa-miR-568
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human immortalized liver cell lines (THLE-2), HCC cell lines (Huh7, SNU-387)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RNF38
Associated microRNA: hsa-miR-568
Biological function: circ_0097009 knockdown blocked HCC cell cloning, proliferation, migration, invasion, angiogenesis and facilitated apoptosis.
Molecular mechanism: circ_0097009/hsa-miR-568/RNF38 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Together, this study indicated that the oncogenic function of circ_0097009 in HCC, and circ_0097009/miR-568/RNF38 axis was expected to be a novel therapeutic option for HCC patients.
Other information
Title:

Hsa_circ_0097009 regulates proliferation, apoptosis, migration and invasion of hepatocellular carcinoma cells via miR-568/RNF38 axis.

Journal: Bratisl Lek Listy
Published: 2023/1/5
PubMed ID: 36598315