circRNA basic information
circBase ID: hsa_circ_0001944
Name: hsa_circ_FIRRE
Synonym: CircFIRRE
Host Gene: hsa-miR-498
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human gastric cancer cell line (AGS, SGC7901)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GSPT1
Associated microRNA: hsa-miR-498
Biological function: Knockdown of hsa_circ_0001944 significantly suppressed the cell proliferation, invasion, and migration.
Molecular mechanism: hsa_circ_0001944/hsa-miR-498/GSPT1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

The present study demonstrates the hsa_circ_0001944/miR-498/GSPT1 axis contributes to GC development. This may provide a target for GC therapy and potential prognostic biomarker.
Other information
Title:

Hsa_circ_0001944 enhanced GSPT1 expression via sponging miR-498 to promote proliferation and invasion of gastric cancer.

Journal: J Clin Lab Anal
Published: 2023/1/5
PubMed ID: 36597856