circRNA basic information
circBase ID: hsa_circ_0026218
Name: hsa_circ_CERS5
Synonym: Circ_0026218
Host Gene: hsa-miR-188-3p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TLR4
Associated microRNA: hsa-miR-188-3p
Biological function: Knockdown of circ_0026218 attenuated ox-LDL-induced dysfunction in HUVECs.
Molecular mechanism: circ_002621/hsa-miR-188-3p/TLR4, NF-kappaB, miRNA sponge
Survival: -
Supported No.:
 2
Description:

Circ_0026218 knockdown attenuated ox-LDL-induced dysfunction in HUVECs via regulating miR-188-3p/TLR4/NF-kB pathway.
Other information
Title:

Circ_0026218 ameliorates oxidized low-density lipoprotein-induced vascular endothelial cell dysfunction by regulating miR-188-3p/TLR4/NF-kappaB pathway.

Journal: Cardiovasc Drugs Ther
Published: 2022/12/31
PubMed ID: 36585554