circRNA basic information
circBase ID: hsa_circ_0006220
Name: hsa_circ_TADA2A
Synonym: Circ_0006220
Host Gene: hsa-miR-342-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal lung cell line BEAS-2B, common NSCLC cell lines (A-549, NCI-H1299), human umbilical vein endothelial cell line (HUVEC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GOT2
Associated microRNA: hsa-miR-342-3p
Biological function: Circ_0006220 silencing inhibited the proliferation, migration, invasion, and angiogenesis but induced the apoptosis of NSCLC cells.
Molecular mechanism: circ_0006220/hsa-miR-342-3p/GOT2 axis, miRNA sponge
Survival: -
Supported No.:
 6
Description:

Circ_0006220 promoted the malignant behaviors of NSCLC cells through mediating the miR-342-3p/GOT2 regulation cascade.
Other information
Title:

Circ_0006220 Contributes to NSCLC Progression through miR-342-3p/GOT2 Axis.

Journal: Ann Thorac Cardiovasc Surg
Published: 2022/12/28
PubMed ID: 36575008