circRNA basic information
circBase ID: hsa_circ_0078200
Name: hsa_circ_TAB2
Synonym: circTAB2
Host Gene: hsa-miR-3142
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human embryonic kidney cells (HEK-293 T), human lung cancer cell lines (NCI-H1299, A549, NCI-H460, NCI-H1588, NCI-H3255), immortalized human bronchial epithelial cells (BEAS-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: GLIS2
Associated microRNA: hsa-miR-3142
Biological function: Gain and loss-of-function assays indicated that circTAB2 could inhibit cell proliferation, migration and invasion.
Molecular mechanism: circTAB2/GLIS2/AKT axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Taken together, circTAB2 serves as an inhibitory role in lung cancer through a novel circTAB2 /miR-3142 /GLIS2 /AKT pathway and could be exploited a novel marker in lung cancer.
Other information
Title:

circTAB2 inhibits lung cancer proliferation, migration and invasion by sponging miR-3142 to upregulate GLIS2.

Journal: Apoptosis
Published: 2022/12/28
PubMed ID: 36574090