circRNA basic information
circBase ID: hsa_circ_0104103
Name: hsa_circ_LACTB
Synonym: circ0104103
Host Gene: hsa-miR-373-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human CRC cell lines (HCT116, HT29, HCT8, SW480, SW620, DLD1, CACO2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: HuR, LACTB, LACTB
Associated microRNA: hsa-miR-373-5p
Biological function: Functional studies revealed that circ0104103 inhibited CRC cell growth, migration, and invasion both in vitro and in vivo.
Molecular mechanism: circ0104103/hsa-miR-373-5p/LACTB axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Taken together, our study revealed that circ0104103 acts as a tumor suppressor and may be a novel biomarker and therapeutic target in CRC.
Other information
Title:

Circular RNA circ0104103 inhibits colorectal cancer progression through interactions with HuR and miR-373-5p.

Journal: Cancer Sci
Published: 2022/12/24
PubMed ID: 36562402