circRNA basic information
circBase ID: hsa_circ_0058608
Name: hsa_circ_SP140L
Synonym: Circ_0058608
Host Gene: hsa-miR-1299
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GBP1
Associated microRNA: hsa-miR-1299
Biological function: Circ_0058608 knockdown inhibited NSCLC cell proliferation and metastasis and also suppressed tumor growth in vivo. circ_0058608 knockdown increased taxol sensitivity by increasing taxol-induced apoptosis in taxol-resistant NSCLC cells
Molecular mechanism: Circ_0058608/hsa-miR-1299/GBP1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0058608 promoted the progression and taxol resistance of NSCLC by regulating the miR-1299/GBP1 axis.
Other information
Title:

Circ_0058608 contributes to the progression and taxol resistance of non-small cell lung cancer by sponging miR-1299 to upregulate GBP1.

Journal: Anticancer Drugs
Published: 2022/12/21
PubMed ID: 36539364