circRNA basic information
circBase ID: hsa_circ_0004689
Name: hsa_circ_SWT1
Synonym: circSWT1
Host Gene: hsa-miR-370-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HBE, A549, NCI-H460, PC-9, H1703, NCI-H1299
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SNAIL
Associated microRNA: hsa-miR-370-3p
Biological function: promote invasion and migration
Molecular mechanism: induced EMT
Survival: -
Supported No.:
 1
Description:

CircSWT1 promoted the invasion, migration, and EMT of NSCLC. CircSWT1 could serve as a potential biomarker and a potential therapeutic target for NSCLC.
Other information
Title:

Circular RNA hsa_circ_0004689 (circSWT1) promotes NSCLC progression via the miR-370-3p/SNAIL axis by inducing cell epithelial-mesenchymal transition (EMT).

Journal: Cancer Med
Published: 2022/12/20
PubMed ID: 36530171