circRNA basic information
circBase ID: hsa_circ_0032704
Name: hsa_circ_TTLL5
Synonym: circTTLL5
Host Gene: hsa-miR-136-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HuH-7, HCCLM3, THLE-2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KIAA1522
Associated microRNA: hsa-miR-136-5p
Biological function: promote cell proliferation and metastasis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

Exosomal circTTLL5 promoted HCC progression through miR-136-5p/KIAA1522 axis, suggesting that blockage of the exosome-mediated transfer of circTTLL5 might be a therapeutic target for HCC.
Other information
Title:

Exosome-mediated circTTLL5 transfer promotes hepatocellular carcinoma malignant progression through miR-136-5p/KIAA1522 axis.

Journal: Pathol Res Pract
Published: 2022/12/19
PubMed ID: 36528986