circRNA basic information
circBase ID: hsa_circ_0026337
Name: hsa_circ_SCN8A
Synonym: CircSCN8A
Host Gene: hsa-miR-1290
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: A549, H1299, NCI-H520, SK-MES-1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: ACSL4
Associated microRNA: hsa-miR-1290
Biological function: cell proliferation and metastasis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circSCN8A represses cell proliferation and metastasis in NSCLC by regulating the miR-1290/ACSL4 axis to induce ferroptosis.
Other information
Title:

CircSCN8A suppresses malignant progression and induces ferroptosis in non-small cell lung cancer by regulating miR-1290/ACSL4 axis.

Journal: Cell Cycle
Published: 2022/12/10
PubMed ID: 36482742