circRNA basic information
circBase ID: -
Name: hsa_circ_FUT8
Synonym: circFUT8
Host Gene: hsa-miR-628-5p
 
 
 
Disease basic information
DO ID:
684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: HCC cell lines (Huh7, HCCLM3, Hep3B, MHCC97H), immortalized human liver epithelial cell line (THLE-3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-628-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
2
Description:

M1 macrophages-derived exosomal miR-628-5p inhibited the m6A modification of circFUT8, inhibiting HCC development.

Other information
Title:

Exosomal miR-628-5p from M1 polarized macrophages hinders m6A modification of circFUT8 to suppress hepatocellular carcinoma progression.

Journal: Cell Mol Biol Lett
Published: 2022/12/7
PubMed ID: 36474147