circRNA_0000491/miR_101b/TGFbetaRI axis in ECM accumulation and fibrosis_associated protein expression levels of mesangial cells, which suggested that circRNA_0000491 may be beneficial for the development of an effective therapeutic target for DN.
A novel identified circular RNA, circ_0000491, aggravates the extracellular matrix of diabetic nephropathy glomerular mesangial cells through suppressing miR_101b by targeting TGFbetaRI.