circRNA basic information
circBase ID: hsa_circ_0001944
Name: hsa_circ_TCONS_l2_00030860
Synonym: circ_0001944
Host Gene: -
 
 
 
Disease basic information
DO ID:
 1240
DO name: leukemia
Disease details: leukemia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: TK6
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

hsa_circ_001944 was able to dissociate HuR and PARP1 binding in HQ-TK6 cells, control PARP1 production, and ultimately alter the PARP1/H-Ras pathway.
Other information
Title:

Hsa_circ_0001944 regulates apoptosis by regulating the binding of PARP1 and HuR in leukemia and malignant transformed cells induced by hydroquinone.

Journal: Environ Toxicol
Published: 2022/12/1
PubMed ID: 36448377