circRNA basic information
circBase ID: hsa_circ_0004488
Name: -
Synonym: circ_0004488
Host Gene: hsa-miR-136
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: cervical cancer cell lines (HeLa, C33A, SiHa), a normal cell line (Ect1/E6E7)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MEX3C
Associated microRNA: hsa-miR-136
Biological function: paclitaxel resistance
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ_0004488 was shown to induce CSC-like features and paclitaxel resistance through the miR-136/MEX3C axis.
Other information
Title:

Circular RNA circ_0004488 Increases Cervical Cancer Paclitaxel Resistance via the miR-136/MEX3C Signaling Pathway.

Journal: J Oncol
Published: 2022/11/29
PubMed ID: 36439901