circRNA basic information
circBase ID: -
Name: hsa_circ_RanGAP1
Synonym: circRanGAP1
Host Gene: hsa-miR-27b-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: PLC/PRF/5, Hep3B, HepG2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NRAS
Associated microRNA: hsa-miR-27b-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circRanGAP1 is a HCC oncogene that function by the miR-27b-3p/NRAS/ERK axis and regulates the infiltration levels of tumor-associated macrophages by sponging miR-27b-3p.
Other information
Title:

circRanGAP1/miR-27b-3p/NRAS Axis may promote the progression of hepatocellular Carcinoma.

Journal: Exp Hematol Oncol
Published: 2022/11/9
PubMed ID: 36348379