circRNA basic information
circBase ID: -
Name: hsa_circ_IRAK1
Synonym: CircIRAK1
Host Gene: hsa-miR-330-5p1
 
 
 
Disease basic information
DO ID:
1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HUVECs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-330-5p1
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

circIRAK1 upregulated TRIM14 by interacting with miR-330-5p, consequently contributing to ox-LDL-induced endothelial cell injury in AS.

Other information
Title:

CircIRAK1 aggravates ox-LDL-induced endothelial cell injury in atherosclerosis via TRIM14 upregulation by binding to miR-330-5p1.

Journal: Clin Hemorheol Microcirc
Published: 2022/11/8
PubMed ID: 36336926